The eight-hour walkout by members of the Vereinigung Cockpit union is the third strike at the German airline in two weeks.
The strike at Munich, Lufthansa’s biggest airport after Frankfurt, is likely to affect 13,500 passengers.
The industrial action will run from 10am to 6pm local time at the airline’s second biggest hub after Frankfurt.
Lufthansa usually operates around 320 flights to and from the airport during that time.
Passengers whose German domestic flights have been cancelled due to the strike may alternatively travel by train with Deutsche Bahn, the airline said.
The pilots aim to increase pressure on Lufthansa in negotiations over an early retirement scheme. They held a strike at its budget carrier Germanwings at the end of August, followed by a walkout at Frankfurt last week.
Lufthansa, which has called on the pilots to return to the negotiating table, said the strike would not result in long-haul flights being cancelled, although there could be some delays.
Sourced from Travel Weekly